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Research Associate - Discovery
Spark Therapeutics, Inc
Job Location: Philadelphia, PA
The Research Associate - Discovery will:
  • With guidance and supervision from the group leader or supervisor, participate in design and execution of high-level molecular biology and protein based assays.
  • Implement new assays or optimize existing assays based on in-depth knowledge of basic laboratory techniques.
  • Participate in sample management activities such as receiving, processing, storage and shipping clinical and preclinical samples.
  • Work with senior staff to ensure the availability of adequate laboratory materials and qualify new reagents, as needed.
  • Maintain accurate, timely and detailed records of work.


  • Utilize advanced molecular biology and immunology based techniques to improve the delivery and the efficacy of gene therapy vectors
  • Design, implement, and troubleshoot experiments, both independently and in collaboration with colleagues, to reach project goals in a fast-paced research environment, with a focus on flexibility and ability to multitask
  • Communicate research and development findings with the other scientists in the team
  • Keep detailed records of scientific findings and accurate inventory of materials and reagents

  • Ability to learn new techniques, perform multiple tasks simultaneously
  • Flexibility to change order of priorities per company evolving needs
  • Ability to work independently after initial training as well as being part of a team
  • Possess self-motivation, adaptability, and a positive attitude
  • Excellent organizational, communication and collaborations skills
  • Keep accurate records, follow instructions, and comply with company policies. Familiarity of Electronic Lab Notebook (ELN) and Laboratory Information Management Systems (LIMS) a plus.

  • BA/BS in biological sciences required
  • Generally has 2-3 years of relevant experience
  • Extensive hands on experience in cloning and molecular biology
  • Hands on experience with PCR and QT-PCR
  • Experience with gene therapy vectors is a plus
  • Experience with Next Generation Sequencing is a plus
  • Experience with ELISA and other immuno-assays is preferred
  • Experience with cell culture and aseptic techniques is preferred


Transforming Patients Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.


How To Apply:
You will be directed to another website for application instructions.
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